3d Rotational Angiography of Transplanted Renal Arteries

Hagen, G. 3D Rotational Angiography of Transplanted Renal Arteries. A Clinical and Experimental Study. 46 pp. Uppsala. ISBN 91-506-1748-6. Th ree-dimensional rotational angiography (3D-RA) is an established method within the fi eld of interventional neuroradiology. Th e method has also a great potential in other areas with a complicated arterial anatomy. Th e purpose of this study was fi rstly to develop an investigative protocol for 3D-RA in renal transplanted patients with threatening allograft failure in diagnosing stenosis in the transplanted renal artery; secondly the protocol was evaluated and compared with a modifi ed protocol including reduced contrast medium load. Furthermore, the advantages of the 3D reconstructions compared to the angiographic images were evaluated, likewise if an extended angle of rotation reduced the artifacts in the 3D reconstructions. Th e two protocols were compared with regard to image quality and acute nephrotoxicity. Th e accuracy of Doppler ultrasonography and the result of percutaneous transluminal angioplasty (PTA) were also assessed. 3D-RA was consecutively performed in 57 renal transplanted patients with suspicion of renal artery stenosis. A signifi cant stenosis was found in 49% of the patients. Th e 3D reconstructions profi led 43% of the transplant renal artery stenoses better than the angiographic images. An extended angle of rotation reduced the artifacts. Th ere was no statistical diff erence regarding image quality between the two protocols, and the renal function was equally aff ected in both protocols. Doppler ultrasonography sensitivity was 100%; specifi city was 48% and positive predictive value 67%. PTA had a technical success rate of 92% and a clinical success rate of 75% after 3 months. 3D-RA is a helpful supplement in cases with complicated vascular anatomy, especially when PTA may be indicated. Th e 3D reconstructions profi le the course of the artery more frequently than the angiographic images and support PTA. Th e 3D reconstructions are degraded of artifacts. Sampling artifacts can be diminished by increased C-arm rotation and increased number of projections. Th e distortions caused by beam hardening remain to be solved.